Risk for Second Nonlymphoid Neoplasms in Chronic Lymphocytic Leukemia

Constantin A. Dasanu, MD, PhD; Doru T. Alexandrescu, MDAbstract Major advances have occurred in understanding the biology, immunology, and modalities of treatment of chronic lymphocytic leukemia (CLL) in the last decade. B-cell CLL is the most common type of leukemia occurring in the US and Western nations. B-cell CLL is characterized by progressive defects in […]

Science and Sensibility: An Interview With Professor Rolf M. Zinkernagel

Science and Sensibility: An Interview With Professor Rolf M. Zinkernagel, Nobel Prize Winner for Medicine 1996 Interviewers: Hrishikesh Satish Kulkarni; Ajit H. Goenka, MBBSInterviewee: Rolf M. Zinkernagel, MD, PhDIntroduction Science is perceived to be the panacea to many of the world's problems. No wonder then that scores of brilliant minds are busy applying time-tested scientific […]

Opioid and Nonopioid Therapies for the Management of Pain

Lynn R. Webster, MD, FACPM, FASAM     IntroductionThe evolving need of pain patients for safe, effective analgesia is driving research into new therapeutic modalities and fresh approaches to familiar treatments. Innovation, involving both opioid and nonopioid pain therapies, dominated discussion at the 23rd Annual Meeting of the American Academy of Pain Medicine held February 7-10 in […]

New Statement on Safety of MRI With CV Devices

News Author: Lisa NainggolanCME Author: Désirée Lie, MD, MSEd The American Heart Association has published a scientific statement on the safety of magnetic resonance imaging (MRI) in patients with cardiovascular devices, which has also been endorsed by the American College of Cardiology, the North American Society for Cardiac Imaging, and the Society for Cardiovascular Magnetic […]

A treatment strategy for NSCLC

Expert OpinionNasser Hanna, MDIndiana UniversityNasser Hanna, MD, is an assistant professor at Indiana University, medical director for their Thoracic Oncology Program, and chair of the thoracic committee for the Hoosier Oncology Group. Recently, WebMD spoke with Dr Hanna about the current treatment options in previously treated NSCLC, treatment decisions in this setting, and the role […]

Guidelines for Perioperative Cardiovascular Evaluation for Patients Considering Noncardiac Surgery

The American College of Cardiology (ACC) and American Heart Association (AHA) have issued a new guideline (last published in 2002) on the perioperative cardiovascular evaluation for patients considering noncardiac surgery. The new algorithm is simpler and gives clinicians more latitude in individualizing decisions, but does not apply to patients who require emergency surgery or who […]

Changing the Paradigm of Anticoagulation Management

Dr. Ancell

Dr. AnsellInterview: Jack Ansell, MDProfessor of MedicineBoston University School of MedicineVice Chairman for Clinical AffairsDepartment of MedicineBoston University Medical CenterBoston, Massachusetts Medscape had the opportunity to discuss laboratory and office-based anticoagulation monitoring with Jack Ansell, MD, Professor of Medicine, Boston University School of Medicine, and Vice Chairman for Clinical Affairs, Department of Medicine, Boston University […]

Fatal Cardiac Tamponade as a Result of a Peripherally Inserted Central Venous Catheter

Fatal Cardiac Tamponade as a Result of a Peripherally Inserted Central Venous Catheter: A Case Report and Review of the Literature R. M. L'E. Orme; M. M. McSwiney; R. F. O. Chamberlain-WebberAbstract and IntroductionAbstract We present a case of fatal cardiac tamponade that occurred in association with a peripherally inserted central catheter (PICC) inserted from […]

An Evidence-Based Algorithm for the Treatment of Neuropathic Pain

Nanna B. Finnerup, MD; Marit Otto, MD; Troels S. Jensen, MD, PhD; Søren H. Sindrup, MD, PhD Abstract Objective: The purpose of this article is to discuss an evidence-based algorithm that can be implemented by the primary care physician in his/her daily clinical practice for the treatment of patients with neuropathic pain conditions. Method: A […]