Factor VII Curbs Bleeding in Non-Hemophiliac Trauma, Surgical Patients

Use of recombinant activated factor VII (rFVIIa) reduces the need for blood transfusion in patients without hemophilia and may also reduce mortality, according to pooled data from randomized placebo-controlled trials involving more than 3000 participants, Canadian researchers report.

First Heart Transplants in Children Following Donor Cardiac Death

US doctors have reported the first experiences of heart transplant in three infants after cardiocirculatory death, rather than brain death, in the donors [1]. Lead author Dr Mark M Boucek (Joe DiMaggio Children's Hospital, Hollywood, FL) told heartwire this was, to his knowledge, the first published account of heart transplant in children after donor cardiac […]

Tibolone Decreases Fracture, Breast Cancer, but Doubles Stroke Risk

Results of a randomized trial show that tibolone (Livial, Organon), approved for treatment of menopausal symptoms, has positive effects on fracture, breast cancer, and possibly colon cancer in women with osteoporosis over the age of 60 years but more than doubled the risk for stroke.