U.S. Lawmakers Probe FDA Approval of Ranbaxy Drugs

Two leading U.S. Democrats said on Tuesday they are investigating whether Food and Drug Administration knowingly allowed the sale of Ranbaxy drugs that may have been backed by fraudulent data. The congressional investigation stems from information released as part of a probe by U.S. law enforcement authorities into whether the Indian drugmaker submitted false data […]

UK Agency Urges Doctors to Cut Antibiotics

British doctors should slash the number of times they prescribe antibiotics for respiratory tract infections because the drugs rarely help, the country's drug cost watchdog said on Wednesday.

Vancomycin Underdosing Very Common in the Obese

More than 70% of obese patients do not receive adequate doses of vancomycin, possibly resulting in subtherapeutic concentrations, according to Dallas-based researchers. Criteria that are more stringent suggest that this may also be true of a much wider group of patients. In the June issue of the American Journal of Medicine, Dr. Ronald G. Hall […]

WellPoint Profit Beats Estimates, Shares Rise

Health insurer WellPoint Inc said on Wednesday profit fell 10 percent, as medical costs ate further into premiums, but its shares rose more than 6 percent as results beat projections, helped by strength in its pharmacy and behavioral health businesses. Although the largest U.S. health insurer by membership tempered its full-year profit and enrollment forecasts, […]

Pulmonary Arterial Hypertension More Severe in Carriers of BMPR2 Mutation

Among patients with pulmonary arterial hypertension (PAH), those with germline mutations in the gene encoding bone morphogenetic protein receptor 2 (BMPR2) present at an earlier age and with more severe hemodynamic compromise, according to findings from a French study. Dr. Marc Humbert of Universite Paris-Sud 11 and colleagues screened 223 consecutive patients with PAH for […]

Growth Hormone Therapy May Decrease Diabetes Risk in Girls With Turner Syndrome

Growth hormone (GH) treatment has beneficial effects on body composition, regional fat deposition and glucose tolerance in girls with Turner syndrome, a study suggests. "We found that GH-treated girls were leaner, with less abdominal fat and normal glucose tolerance compared with never-treated girls in the current study and compared with Turner syndrome girls in studies […]