Risk Factors Identified for Transfusion-Related Acute Lung Injury in Critically Ill Patients

By Will Boggs, MDTransfusion factors and patient characteristics contribute to the risk of acute lung injury (ALI) following blood transfusions in critically ill patients, according to a report in the November 1st issue of the American Journal of Respiratory and Critical Care Medicine. "Critically ill patients, their families, and physicians need to be aware that […]

Expert Viewpoint: William J. Gradishar, MD

Professor, Division of Hematology and Medical OncologyNorthwestern UniversityThe Feinberg School of MedicineChicago, IL William J. Gradishar, MD, is Professor of Medicine in the Division of Hematology and Medical Oncology at the Feinberg School of Medicine at Northwestern University in Chicago, Illinois, and a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. […]

Risks of Transfusion

Bruce D. Spiess, MD, FAHAIntroductionBlood transfusion has evolved into a mainstay medical therapy. It has never undergone efficacy and safety testing the way in which a drug would be tested for approval by the US Food and Drug Administration.[1,2] Today, some 107 years after Karl Landsteiner discovered the ABO histocompatibility antigens, we are still learning […]

Characteristics of Patients Prescribed Angiotensin-Converting Enzyme Inhibitors

Characteristics of Patients Prescribed Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, or the Combination at an Urban Medical CenterGhania Masri, MD; Kristi Bledsoe, PharmD; Carlos Palacio, MD Abstract Background: The realization that angiotensin-converting enzyme (ACE) inhibitors do not provide complete blockade of angiotensin II synthesis has resulted in an increased use of combinations of ACE inhibitors […]

ACP Addresses Potential Outcomes of Pay for Performance

News Author: Laurie Barclay, MDCME Author: Charles Vega, MD The American College of Physicians has issued recommendations to offset the potential adverse effects of pay-for-performance programs and to redirect the focus to the patient. Their position paper, which highlights the ethical implications of pay for performance and potential effects on the clinician-patient relationship, is published […]

Risk for Second Nonlymphoid Neoplasms in Chronic Lymphocytic Leukemia

Constantin A. Dasanu, MD, PhD; Doru T. Alexandrescu, MDAbstract Major advances have occurred in understanding the biology, immunology, and modalities of treatment of chronic lymphocytic leukemia (CLL) in the last decade. B-cell CLL is the most common type of leukemia occurring in the US and Western nations. B-cell CLL is characterized by progressive defects in […]

Science and Sensibility: An Interview With Professor Rolf M. Zinkernagel

Science and Sensibility: An Interview With Professor Rolf M. Zinkernagel, Nobel Prize Winner for Medicine 1996 Interviewers: Hrishikesh Satish Kulkarni; Ajit H. Goenka, MBBSInterviewee: Rolf M. Zinkernagel, MD, PhDIntroduction Science is perceived to be the panacea to many of the world's problems. No wonder then that scores of brilliant minds are busy applying time-tested scientific […]