A New Dawn in Cardio and Vascular Protection V. Cardiovascular High-Risk Patients: Treat to Protect
Cardiovascular and cerebrovascular diseases are a major cause of death and disability worldwide; around 7.1 million deaths, as well as two thirds of strokes and one half of ischemic heart disease, are attributable to nonoptimal blood pressure control. Large outcome trials have demonstrated that blockade of the renin-angiotensin system (RAS) is an important approach to […]
Bone Biopsy Improves Medical Therapy of Diabetic Foot Osteomyelitis
In diabetic patients undergoing medical management of foot osteomyelitis, bone culture-based antibiotic therapy improves the chances of successful treatment, according to findings published in the April issue of Diabetes Care. "The question of surgical versus nonsurgical treatment for diabetic patients with osteomyelitis of the foot remains subject to debate," Dr. Eric Senneville, of Dron Hospital, […]
Efficacy of Lasers and PDT for the Treatment of Acne Vulgaris
Abstract Acne vulgaris can represent a therapeutic challenge in terms of managing ongoing symptoms and preventing scar formation. While the copious variations of available treatments address milder forms of the disease, until recently, therapies for resistant or moderate-to-severe forms were limited to systemic agents that were accompanied by potentially severe side-effects. With the addition of […]
Physician-Directed Home Care Reduces COPD Exacerbations in Elderly
A system employing hospital levels of care delivered at home to elderly patients with chronic obstructive pulmonary disease (COPD) exacerbations provides results superior to those with inpatient treatment, according to Italian and US researchers.
Expert Viewpoint: William J. Gradishar, MD
Professor, Division of Hematology and Medical OncologyNorthwestern UniversityThe Feinberg School of MedicineChicago, IL William J. Gradishar, MD, is Professor of Medicine in the Division of Hematology and Medical Oncology at the Feinberg School of Medicine at Northwestern University in Chicago, Illinois, and a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. […]
Models Predict Success With Growth Hormone Treatment
Mathematical models, particularly those incorporating both growth and endocrine data, can predict which short children will benefit from treatment with growth hormone (GH), according to a new study.
Characteristics of Patients Prescribed Angiotensin-Converting Enzyme Inhibitors
Characteristics of Patients Prescribed Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, or the Combination at an Urban Medical CenterGhania Masri, MD; Kristi Bledsoe, PharmD; Carlos Palacio, MD Abstract Background: The realization that angiotensin-converting enzyme (ACE) inhibitors do not provide complete blockade of angiotensin II synthesis has resulted in an increased use of combinations of ACE inhibitors […]
FDA Safety Changes: Pexeva, Vfend, Suprane
News Author: Yael WaknineCME Author: Yael Waknine The US Food and Drug Administration (FDA) has approved safety labeling revisions to advise of the risk for serotonin syndrome in patients receiving concomitant treatment with paroxetine mesylate and triptans, drug interactions between voriconazole and efavirenz requiring dose adjustments for both drugs when used concomitantly, and the risk […]
Guidelines Updated for Antiretroviral Therapy in Teens and Adults With HIV-1 Infection
News Author: Laurie Barclay, MDCME Author: Hien T. Nghiem, MD On December 1, the Department of Health and Human Services (DHHS) issued updated guidelines for the use of antiretroviral agents in teens and adults infected with human immunodeficiency virus type 1 (HIV-1).
Risk for Second Nonlymphoid Neoplasms in Chronic Lymphocytic Leukemia
Constantin A. Dasanu, MD, PhD; Doru T. Alexandrescu, MDAbstract Major advances have occurred in understanding the biology, immunology, and modalities of treatment of chronic lymphocytic leukemia (CLL) in the last decade. B-cell CLL is the most common type of leukemia occurring in the US and Western nations. B-cell CLL is characterized by progressive defects in […]
