New Data Will Help Guide Prescribing of Celecoxib

A new meta-analysis of six randomized trials involving the cyclooxygenase-2 (COX-2) inhibitor celecoxib (Celebrex, Pfizer) should help direct physicians who still want to prescribe this drug [1]. Dr Scott D Solomon (Brigham and Women's Hospital, Boston, MA) presented the findings of the cross-trial safety analysis at a late-breaking trials session here at the American College […]

Oral Contrast for Abdominal CT: How Important Is It and How Long Does It Take?

QuestionHow important is oral contrast material to the accuracy of an abdominal computed tomography (CT), and how long does it really take to reach its intended target? Response from Joseph R. Lex Jr., MDAssociate Professor, Department of Emergency Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania

Bone Biopsy Improves Medical Therapy of Diabetic Foot Osteomyelitis

In diabetic patients undergoing medical management of foot osteomyelitis, bone culture-based antibiotic therapy improves the chances of successful treatment, according to findings published in the April issue of Diabetes Care. "The question of surgical versus nonsurgical treatment for diabetic patients with osteomyelitis of the foot remains subject to debate," Dr. Eric Senneville, of Dron Hospital, […]

Efficacy of Lasers and PDT for the Treatment of Acne Vulgaris

Abstract Acne vulgaris can represent a therapeutic challenge in terms of managing ongoing symptoms and preventing scar formation. While the copious variations of available treatments address milder forms of the disease, until recently, therapies for resistant or moderate-to-severe forms were limited to systemic agents that were accompanied by potentially severe side-effects. With the addition of […]

Combination Low-Dose DFMO and Sulindac Reduce Recurrence of Colorectal Adenomas

Combining low-dose difluoromethylornithine (DFMO) and the nonsteroidal anti-inflammatory drug (NSAID) sulindac lowers the risk for recurrent colorectal adenomas. The results of the phase 3 randomized trial, which were reported here at the American Association for Cancer Research 2008 Annual Meeting, showed that among patients who received the active drug combination, there was a 70% decrease […]

Safe STEP Program Effective for Getting Older Hospitalized Patients Home

An innovative program helps elderly patients avoid the pitfalls associated with making the transition from hospital to home, Param Dedhia, MD, instructor in the Collaborative Internal Medicine Service, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, reported here at Hospital Medicine 2008, the Society of Hospital Medicine annual meeting.

Transparency in Adverse Event Reporting Pleases Patients

Hospitalized patients who suffer an adverse event may learn little about it from medical personnel, especially if the event is preventable, according to findings presented here at Hospital Medicine 2008, the Society of Hospital Medicine annual meeting.