Aggressive Malpractice Environments Dictate How, Not Where, Neurosurgeons Practice
New research suggests aggressive medical malpractice environments do not influence where neurosurgeons practice but may cause them to limit their practice, which may result in a critical erosion of care in some of the most critically neurological patients.
New Data Will Help Guide Prescribing of Celecoxib
A new meta-analysis of six randomized trials involving the cyclooxygenase-2 (COX-2) inhibitor celecoxib (Celebrex, Pfizer) should help direct physicians who still want to prescribe this drug [1]. Dr Scott D Solomon (Brigham and Women's Hospital, Boston, MA) presented the findings of the cross-trial safety analysis at a late-breaking trials session here at the American College […]
Blood Substitutes Linked to Deaths, MI; FDA Should Have Acted Sooner to Stop Trials, Researchers Say
People treated with blood substitutes in clinical trials over the past two decades were 30% more likely to die and had almost a threefold higher rate of myocardial infarction (MI) than patients in control groups, a new meta-analysis suggests [1]. Even more damning, the authors of the study say that the US Food and Drug […]
Occupational Exposure to Formaldehyde Linked to Increased ALS Risk
No significant association between ALS and pesticide, herbicide exposure. Preliminary results from a large prospective population-based study has linked occupational exposure to formaldehyde, with an increased rate of amyotrophic lateral sclerosis (ALS).
Oral Contrast for Abdominal CT: How Important Is It and How Long Does It Take?
QuestionHow important is oral contrast material to the accuracy of an abdominal computed tomography (CT), and how long does it really take to reach its intended target? Response from Joseph R. Lex Jr., MDAssociate Professor, Department of Emergency Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania
Bone Biopsy Improves Medical Therapy of Diabetic Foot Osteomyelitis
In diabetic patients undergoing medical management of foot osteomyelitis, bone culture-based antibiotic therapy improves the chances of successful treatment, according to findings published in the April issue of Diabetes Care. "The question of surgical versus nonsurgical treatment for diabetic patients with osteomyelitis of the foot remains subject to debate," Dr. Eric Senneville, of Dron Hospital, […]
Efficacy of Lasers and PDT for the Treatment of Acne Vulgaris
Abstract Acne vulgaris can represent a therapeutic challenge in terms of managing ongoing symptoms and preventing scar formation. While the copious variations of available treatments address milder forms of the disease, until recently, therapies for resistant or moderate-to-severe forms were limited to systemic agents that were accompanied by potentially severe side-effects. With the addition of […]
Combination Low-Dose DFMO and Sulindac Reduce Recurrence of Colorectal Adenomas
Combining low-dose difluoromethylornithine (DFMO) and the nonsteroidal anti-inflammatory drug (NSAID) sulindac lowers the risk for recurrent colorectal adenomas. The results of the phase 3 randomized trial, which were reported here at the American Association for Cancer Research 2008 Annual Meeting, showed that among patients who received the active drug combination, there was a 70% decrease […]
Safe STEP Program Effective for Getting Older Hospitalized Patients Home
An innovative program helps elderly patients avoid the pitfalls associated with making the transition from hospital to home, Param Dedhia, MD, instructor in the Collaborative Internal Medicine Service, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, reported here at Hospital Medicine 2008, the Society of Hospital Medicine annual meeting.
Transparency in Adverse Event Reporting Pleases Patients
Hospitalized patients who suffer an adverse event may learn little about it from medical personnel, especially if the event is preventable, according to findings presented here at Hospital Medicine 2008, the Society of Hospital Medicine annual meeting.